Varicocele
Varicocele is a common condition characterised by the enlargement of veins within the scrotum. It is more common on the left side but can affect both sides. Varicoceles develop when the valves within the veins that regulate blood flow become weakened or dysfunctional, causing blood to pool and the veins to swell. This pooling of blood raises the temperature within the scrotum, which can negatively impact sperm production and quality. Varicoceles are a leading cause of male infertility, contributing to around 40% of cases among men experiencing difficulties with conception. Additionally, varicocele prevalence is even higher, as high as 80%, amongst men with secondary infertility, which is those who have previously fathered a child and are having trouble conceiving again.
How is a varicocele diagnosed
A varicocele is typically diagnosed through a combination of medical history review, physical examination, and diagnostic imaging. A scrotal ultrasound will help to confirm the presence, size and severity of a varicocele.
It may be possible to have these assessments through your GP or the NHS however access to fertility related varicocele services can be limited. It's essential to consult with a healthcare professional for proper evaluation and management of varicocele-related concerns.
Varicoceles are typically graded from 1 to 3 based on their size and severity following a physical examination or diagnostic imaging.
A healthcare provider, typically a urologist or fertility specialist, can evaluate and grade a varicocele during a physical examination and provide appropriate recommendations for further evaluation or treatment if necessary.
Subclinical varicocele, not visible or palpable on physical examination, but detectable by diagnostic imaging such as ultrasound.
Palpable varicocele that can be felt when the patient is in an upright position but not visible without Valsalva manoeuvre (increased abdominal pressure).
Palpable and visible varicocele, even without the need for Valsalva manoeuvre.
How does a varicocele affect fertility?
Not all varicoceles cause fertility problems, and the extent of their impact can vary from person to person. Evaluation by a healthcare provider, typically a urologist or fertility specialist, can help determine the severity of the varicocele and its potential effects on fertility.
Increased scrotal temperature
The pooling of blood in the veins of the scrotum associated with varicoceles can raise the temperature in the testicles which can impair sperm production (spermatogenesis) and decrease sperm quality.
Hormonal imbalance
Varicoceles may disrupt the normal hormonal balance affecting sperm production and maturation.
Venous congestion and hypoxia
Venous congestion caused by varicoceles can lead to reduced oxygen supply (hypoxia) to the testicles, which may damage sperm-producing cells (spermatocytes) and impair sperm function.
Oxidative stress
Varicoceles can increase oxidative stress within the testicles, resulting in the production of reactive oxygen species (ROS) that can damage sperm DNA and cell membranes, leading to decreased sperm quality and viability.
Altered sperm parameters
Varicoceles may lead to abnormalities in sperm parameters, including decreased sperm count, motility, and morphology, which can reduce the chances of fertilisation and successful conception.
If you suspect you have a varicocele or are experiencing symptoms such as scrotal pain, discomfort, or swelling, you should see your GP in the first instance.
Your GP may be able to carry out a physical examination and may be able to refer you for a testicular ultrasound however there is no provision for this service on the NHS for fertility reasons alone.
Therefore, most men have to source a scan privately or it will be requested through a urologist / andrologist.
At testhim we have teamed up with ultrasound direct to allow men to access testicular scanning services at various sites across the UK for a quick, easy and affordable scan. These are available via our store.
If you suspect you have a varicocele or are experiencing symptoms such as scrotal pain, discomfort, or swelling, you should see your GP in the first instance.
You may also want to consider seeing a Urologist or Andrologist for further assessments.
Urologists specialise in diagnosing and treating conditions related to the urinary tract and male reproductive system, including varicoceles and may offer surgical solutions to varicocele. They will also be able to offer further diagnostics such as sperm DNA fragmentation testing.
If you’re considering a varicocele embolisation then you will need to see an interventional radiologist. This is a medical doctor who specialises in performing minimally invasive procedures using imaging guidance, such as X-rays, ultrasound, or CT scans, to diagnose and treat various conditions.
Varicocele treatment, particularly surgical procedures such as varicocelectomy, can involve some discomfort or pain during the recovery period. The extent of discomfort can vary depending on factors such as the type of procedure performed, individual pain tolerance, and the presence of any complications.
Minimally invasive procedures such as varicocele embolisation may involve less pain and a shorter recovery period compared to traditional surgical approaches. However, some patients may still experience mild discomfort or soreness following the procedure.
While varicocele treatment has been shown to improve fertility outcomes in some cases, it does not guarantee success for every individual. The impact of varicocele treatment on fertility depends on various factors, including the severity of the varicocele, the presence of other infertility factors, and individual characteristics such as age and overall health.
Studies have suggested that varicocele repair may lead to improvements in sperm parameters, such as sperm count, motility, morphology and DNA fragmentation, as well as pregnancy rates in couples experiencing infertility due to varicoceles. However, the degree of improvement and the likelihood of achieving pregnancy vary from person to person.
It's important to have realistic expectations about the outcomes of varicocele treatment and to understand that success cannot be guaranteed, and it will take several months for your sperm health to improve.
It's essential to undergo a comprehensive evaluation by a healthcare provider, typically a urologist or fertility specialist, who can assess your specific situation, discuss treatment options, and provide personalised recommendations based on your individual situation.
Varicoceles can be treated through various approaches, depending on factors such as the severity of symptoms, impact on fertility, level of DNA fragmentation and the overall fertility history.
Lifestyle changes including wearing supportive underwear such as cool beans underwear, avoiding prolonged sitting or standing, and practicing scrotal elevation whilst lying down (again with cool beans underwear) may help alleviate symptoms and improve blood flow in the affected veins.
Medical / surgical interventions could include varicocelectomy or embolisation.
Varicocelectomy is a surgical procedure performed to ligate (tie off) or remove the affected veins, thus redirecting blood flow away from the varicocele. This procedure can be performed using various techniques, including open surgery, laparoscopic surgery, or microsurgery.
Varicocele embolisation is a minimally invasive procedure performed by an interventional radiologist. During this procedure, a catheter is inserted into a vein in the groin or neck, and a contrast dye is injected to highlight the varicocele. Embolisation material, such as coils or sclerosing agents, are then inserted to block off the varicocele, redirecting blood flow and reducing symptoms.
The choice of treatment depends on individual factors such as the severity of symptoms, impact on fertility, and personal preferences. A healthcare provider, typically a urologist or fertility specialist, can evaluate the specific circumstances and recommend the most appropriate treatment option.
Men with varicoceles may benefit from undergoing a sperm DNA fragmentation test, especially if they are experiencing infertility or have concerns about their fertility. Varicoceles are known to contribute to sperm DNA damage, and assessing DNA fragmentation can provide valuable insights into the severity of the condition and its potential impact on fertility outcomes. By identifying elevated levels of DNA fragmentation, individuals and their healthcare providers can make informed decisions about treatment options and interventions to improve sperm quality and enhance fertility potential. Therefore, considering a sperm DNA fragmentation test alongside the evaluation of varicoceles can be beneficial for comprehensive fertility assessment and management.
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